Mouse Production

  Transgenic Mouse Production

(click on any tissue system or line for more details)

For details on the construction of transgenes, click here.

In production
Analysis and confirmation
Available
Smooth muscle system (acta2 promoter):
B6: acta2-Optoa1AR-IRES-lacZ

 Jax# 028346
B7: acta2-Optob2AR-IRES-lacZ  √  √ Jax# 028347
B8: acta2-CatCh-IRES-lacZ  √  √ Jax# 028348
B3: acta2-RCaMP1.07  √  √ Jax# 028345
B19: acta2-GCAMP2*  √  √  Jax# 025405
B14: acta2-GCaMP-GR*  √  √   Jax# 025406
B25: acta2-GCaMP-ER  √  √  Jax# 032886
B34: acta2-GCaMP8.1-mVermilion  √  √  Jax# 032887
 Cardiac and venous system (αMHC, HCN4, Cdh5, mesp1, Cx40 and POSTN promoters):
B5: αMHC-CatCh-IRES-lacZ  √  Jax# 030334
B4: αMHC-GCaMP8 Jax# 033341
B17: HCN4-CatCh-IRES-lacZ  Jax# 033344
B10: HCN4-GCaMP8 Jax# 028344
B20: Cdh5-GCaMP8  √ Jax# 033342
B26: Cdh5-Optoα1AR-IRES-lacZ  √  Jax# 033343
B27: Cdh5-optoβ2AR-IRES-lacZ  Jax# 032889
B28: Cdh5-CatCh-IRES-lacZ  Jax# 033345
mesp1-mCherry*  Jax# 025618
B39: Cx40-GCaMP2*  Jax# 025404
B15: Cx40-GCaMP-GR* Jax# 030333
Nervous system (DBH, ChAT, gfap and Aldh1L1 promoters):
B13: dbh-GCaMP8
B16: dbh-CatCh-IRES-lacZ indicate interest
B36: Aldh1L1-optoα1AR-IRES-lacZ  √  indicate interest
Widespread expression:
 B40: pCAGGS-GCaMP2*  JAX# 025619
Immune system (Lck promoter):
B22: Lck-optoα1AR-IRES-lacZ   √  indicate interest
Lung Epithelium (pdpn, SP-C, FoxJ1 and CCSP promoters):
B23: SP-C-GCaMP8  √ Jax# 032885
B35: FoxJ1-GCaMP8.1  √ Jax# 032888
*previously developed in the Kotlikoff Laboratory

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