Mouse Production

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  Transgenic Mouse Production

(click on any tissue system or line for more details)

For details on the construction of transgenes, click here.

In production
Analysis and confirmation
Available
Smooth muscle system (acta2 promoter):
acta2-Optoa1AR-IRES-lacZ

acta2-Optob2AR-IRES-lacZ  √  √ request mice
acta2-CatCh-IRES-lacZ  √  √ request mice
acta2-RCaMP1.07  √  √ request mice
acta2-GCAMP2*  √  √  Jax# 25405
acta2-GCaMP-GR*  √  √   Jax# 25406
 Cardiac and venous system (αMHC, HCN4 and Cdh5 promoters):
αMHC-CatCh-IRES-lacZ  √  request mice
αMHC-GCaMP8 request mice
HCN4-CatCh-IRES-lacZ  request mice
HCN4-GCaMP8 request mice
Cdh5-GCaMP8  √ request mice
Cdh5-Optoα1AR-IRES-lacZ
Cdh5-optoβ2AR-IRES-lacZ
Cdh5-CatCh-IRES-lacZ
Cdh5-GCaMP8-mVermillion
mesp1-mCherry*  Jax# 25618
Cx40-GCaMP2*  Jax# 25404
Cx40-GCaMP-GR* request mice
POSTN-GCaMP8
Nervous system (DBH, ChAT and gfap promoters):
ChAT-GCaMP8
dbh-GCaMP8
dbh-CatCh-IRES-lacZ
gfap-GCaMP-GR*
Ubiquitous expression:
 pCAGGS-GCaMP2*  JAX# 25619
Immune system (Lck promoter):
Lck-optoα1AR-IRES-lacZ
Lck-GCaMP8
Lung Epithelium (pdpn, SP-C, FoxJ1 and CCSP promoters):
SP-C-GCaMP8
pdpn-GCaMP8
*previously developed in the Kotlikoff Laboratory

 

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