Transgenic Mouse Production(click on any tissue system or line for more details) For details on the construction of transgenes, click here. |
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In production |
Analysis and confirmation |
Available |
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Smooth muscle system (acta2 promoter):
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| B6: acta2-Optoa1AR-IRES-lacZ | √ |
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request mice |
| B7: acta2-Optob2AR-IRES-lacZ | √ | √ | request mice |
| B8: acta2-CatCh-IRES-lacZ | √ | √ | request mice |
| B3: acta2-RCaMP1.07 | √ | √ | request mice |
| B19: acta2-GCAMP2* | √ | √ | Jax# 25405 |
| B14: acta2-GCaMP-GR* | √ | √ | Jax# 25406 |
| B25: acta2-GCaMP-ER | √ | ||
| B34: acta2-GCaMP8.1-mVermilion | √ | √ | request mice |
Cardiac and venous system (αMHC, HCN4, Cdh5, mesp1, Cx40 and POSTN promoters): |
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| B5: αMHC-CatCh-IRES-lacZ | √ | √ | request mice |
| B4: αMHC-GCaMP8 | √ | √ | request mice |
| B17: HCN4-CatCh-IRES-lacZ | √ | √ | request mice |
| B10: HCN4-GCaMP8 | √ | √ | request mice |
| B20: Cdh5-GCaMP8 | √ | √ | request mice |
| B26: Cdh5-Optoα1AR-IRES-lacZ | √ | √ | request mice |
| B27: Cdh5-optoβ2AR-IRES-lacZ | √ | √ | request mice |
| B28: Cdh5-CatCh-IRES-lacZ | √ | √ | request mice |
| B29: Cdh5-GCaMP8-mVermillion | √ | ||
| mesp1-mCherry* | √ | √ | Jax# 25618 |
| B39: Cx40-GCaMP2* | √ | √ | Jax# 25404 |
| B15: Cx40-GCaMP-GR* | √ | √ | request mice |
| B30: POSTN-GCaMP8 | √ | ||
| B31: POSTN-CatCh-IRES-lacZ | √ | ||
Nervous system (DBH, ChAT, gfap and Aldh1L1 promoters): |
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| B12: ChAT-GCaMP8 | √ | ||
| B13: dbh-GCaMP8 | √ | ||
| B16: dbh-CatCh-IRES-lacZ | √ | ||
| B11: gfap-GCaMP-GR* | √ | ||
| B21: CGRP-GCaMp8 | √ | ||
| B36: Aldh1L1-optoα1AR-IRES-lacZ | √ | ||
Widespread expression: |
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| B40: pCAGGS-GCaMP2* | √ | √ | JAX# 25619 |
| B18: PDGFRα-GCaMP8 | √ | ||
Immune system (Lck promoter): |
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| B22: Lck-optoα1AR-IRES-lacZ | √ | ||
| B32: Lck-GCaMP8 | √ | ||
| B37: Ly6G-optoα1AR-IRES-mVermilion | √ | ||
| B38: Ly6G-optoβ2AR-IRES-mVermilion | √ | ||
Lung Epithelium (pdpn, SP-C, FoxJ1 and CCSP promoters): |
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| B23: SP-C-GCaMP8 | √ | √ | request mice |
| B24: pdpn-GCaMP8 | √ | ||
| B35: FoxJ1-GCaMP8.1 | √ | ||
| *previously developed in the Kotlikoff Laboratory | |||