Transgenic Mouse Production(click on any tissue system or line for more details) For details on the construction of transgenes, click here. |
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In production |
Analysis and confirmation |
Available |
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Smooth muscle system (acta2 promoter):
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| acta2-Optoa1AR-IRES-lacZ | √ |
√ |
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| acta2-Optob2AR-IRES-lacZ | √ | √ | request mice |
| acta2-CatCh-IRES-lacZ | √ | √ | request mice |
| acta2-RCaMP1.07 | √ | √ | request mice |
| acta2-GCAMP2* | √ | √ | Jax# 25405 |
| acta2-GCaMP-GR* | √ | √ | Jax# 25406 |
Cardiac and venous system (αMHC, HCN4 and Cdh5 promoters): |
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| αMHC-CatCh-IRES-lacZ | √ | √ | request mice |
| αMHC-GCaMP8 | √ | √ | request mice |
| HCN4-CatCh-IRES-lacZ | √ | √ | request mice |
| HCN4-GCaMP8 | √ | √ | request mice |
| Cdh5-GCaMP8 | √ | √ | request mice |
| Cdh5-Optoα1AR-IRES-lacZ | √ | ||
| Cdh5-optoβ2AR-IRES-lacZ | √ | √ | |
| Cdh5-CatCh-IRES-lacZ | √ | √ | |
| Cdh5-GCaMP8-mVermillion | √ | √ | |
| mesp1-mCherry* | √ | √ | Jax# 25618 |
| Cx40-GCaMP2* | √ | √ | Jax# 25404 |
| Cx40-GCaMP-GR* | √ | √ | request mice |
| POSTN-GCaMP8 | √ | √ | |
Nervous system (DBH, ChAT and gfap promoters): |
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| ChAT-GCaMP8 | √ | ||
| dbh-GCaMP8 | √ | ||
| dbh-CatCh-IRES-lacZ | √ | ||
| gfap-GCaMP-GR* | √ | ||
Ubiquitous expression: |
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| pCAGGS-GCaMP2* | √ | √ | JAX# 25619 |
Immune system (Lck promoter): |
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| Lck-optoα1AR-IRES-lacZ | √ | ||
| Lck-GCaMP8 | √ | ||
Lung Epithelium (pdpn, SP-C, FoxJ1 and CCSP promoters): |
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| SP-C-GCaMP8 | √ | ||
| pdpn-GCaMP8 | √ | ||
| *previously developed in the Kotlikoff Laboratory | |||