Mouse Production

  Transgenic Mouse Production

(click on any tissue system or line for more details)

For details on the construction of transgenes, click here.

In production
Analysis and confirmation
Smooth muscle system (acta2 promoter):
B6: acta2-Optoa1AR-IRES-lacZ

 Jax# 28346
B7: acta2-Optob2AR-IRES-lacZ  √  √ Jax# 28347
B8: acta2-CatCh-IRES-lacZ  √  √ Jax# 28348
B3: acta2-RCaMP1.07  √  √ Jax# 28345
B19: acta2-GCAMP2*  √  √  Jax# 25405
B14: acta2-GCaMP-GR*  √  √   Jax# 25406
B25: acta2-GCaMP-ER  √  √  request mice
B34: acta2-GCaMP8.1-mVermilion  √  √  request mice
 Cardiac and venous system (αMHC, HCN4, Cdh5, mesp1, Cx40 and POSTN promoters):
B5: αMHC-CatCh-IRES-lacZ  √  request mice
B4: αMHC-GCaMP8 request mice
B17: HCN4-CatCh-IRES-lacZ  request mice
B10: HCN4-GCaMP8 Jax# 28344
B20: Cdh5-GCaMP8  √ request mice
B26: Cdh5-Optoα1AR-IRES-lacZ  √  request mice
B27: Cdh5-optoβ2AR-IRES-lacZ  request mice
B28: Cdh5-CatCh-IRES-lacZ  request mice
mesp1-mCherry*  Jax# 25618
B39: Cx40-GCaMP2*  Jax# 25404
B15: Cx40-GCaMP-GR* Jax# 30333
Nervous system (DBH, ChAT, gfap and Aldh1L1 promoters):
B13: dbh-GCaMP8
B16: dbh-CatCh-IRES-lacZ indicate interest
B36: Aldh1L1-optoα1AR-IRES-lacZ  √  indicate interest
Widespread expression:
 B40: pCAGGS-GCaMP2*  JAX# 25619
Immune system (Lck promoter):
B22: Lck-optoα1AR-IRES-lacZ   √  indicate interest
Lung Epithelium (pdpn, SP-C, FoxJ1 and CCSP promoters):
B23: SP-C-GCaMP8  √ request mice
B35: FoxJ1-GCaMP8.1  √ request mice
*previously developed in the Kotlikoff Laboratory


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